Gene-regulatory interactions in neural crest evolution and development

被引:347
作者
Meulemans, D [1 ]
Bronner-Fraser, M [1 ]
机构
[1] CALTECH, Pasadena, CA 91125 USA
关键词
D O I
10.1016/j.devcel.2004.08.007
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
In this review, we outline the gene-regulatory interactions driving neural crest development and compare these to a hypothetical network operating in the embryonic ectoderm of the cephalochordate amphioxus. While the early stages of ectodermal patterning appear conserved between amphioxus and vertebrates, later activation of neural crest-specific factors at the neural plate border appears to be a vertebrate novelty. This difference may reflect co-option of genetic pathways which conferred novel properties upon the evolving vertebrate neural plate border, potentiating the evolution of definitive neural crest.
引用
收藏
页码:291 / 299
页数:9
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