Potential drug delivery systems from maleic anhydride copolymers and phenothiazine derivatives

被引：23

作者：

Bacu, E

Chitanu, GC

Couture, A

Grandclaudon, P

Singurel, G

Carpov, A

机构：

[1] Romanian Acad, Petru Poni Inst Macromol Chem, Dept Bioact & Biocompatible Polymers, RO-6600 Iasi, Romania

[2] Al I Cuza Univ, Fac Chem, Dept Organ Chem, RO-6600 Iasi, Romania

[3] Univ Sci & Technol Lille 1, UPRES A 8009, Chim Organ Phys Lab, F-59655 Villeneuve Dascq, France

[4] Al I Cuza Univ, Fac Phys, Dept Opt Spect, RO-6600 Iasi, Romania

来源：

EUROPEAN POLYMER JOURNAL | 2002年 / 38卷 / 08期

关键词：

maleic copolymers; phenothiazine; polymer-drug conjugates;

D O I：

10.1016/S0014-3057(02)00040-X

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

New functionalized derivatives of phenothiazine containing amino or hydroxy groups with potential pharmacological properties were synthesized and characterized. They were reacted with maleic anhydride copolymers in order to obtain conjugates which can be used as controlled-release systems. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1509 / 1513

页数：5

共 18 条

[1]

Bâcu E, 1999, REV ROUM CHIM, V44, P231

[2]

BACU E, 1996, SULFUR SILICON, V108, P231

[3]

BACU E, 1999, SULFUR SILICON, V149, P207

[4]

Bacu Elena, 1997, Annales Pharmaceutiques Francaises, V55, P269

[5] BIOLOGICALLY-ACTIVE SYNTHETIC-POLYMERS [J].

BRESLOW, DS .

PURE AND APPLIED CHEMISTRY, 1976, 46 (2-4) :103-113

[6] MECHANISM OF ALTERNATING COPOLYMERIZATION OF VINYL-ACETATE AND MALEIC-ANHYDRIDE [J].

CAZE, C ;

LOUCHEUX, C .

JOURNAL OF MACROMOLECULAR SCIENCE-CHEMISTRY, 1975, A 9 (01) :29-43

[7] Review: Analysis and characterization of maleic copolymers [J].

Chitanu, GC ;

Zaharia, LI ;

Carpov, A .

INTERNATIONAL JOURNAL OF POLYMER ANALYSIS AND CHARACTERIZATION, 1997, 4 (01) :1-20

[8]

CHITANU GC, 2001, CARPOV A ROM

[9]

CSAKVARI E, 1981, POLYM BULL, V5, P413

[10]

CULBERTSON BMM, 1987, POLYM SCI ENG, V14, P225

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