Light-Driven Enantioselective Organocatalysis

被引：146

作者：

Mueller, Christiane ^{[1
]}

Bauer, Andreas ^{[1
]}

Bach, Thorsten ^{[1
]}

机构：

[1] Tech Univ Munich, Lehrstuhl Organ Chem 1, D-85747 Garching, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 36期

关键词：

cycloadditions; enantioselectivity; organocatalysis; photochemistry; sensitizers; ASYMMETRIC CATALYSIS; MOLECULAR-OXYGEN; PHOTOCYCLOADDITION; CHIRALITY; CHEMISTRY;

D O I：

10.1002/anie.200901603

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Collection, sensitization, and selection are the tasks of the organocatalyst 1, which it fulfills almost perfectly in the photochemical conversion of quinolone 2. It collects light (λ>350 nm), transfers its energy to the substrate, and induces a high enantioselectivity. Even with only 10 mol % of catalyst, a yield of 90 % was achieved with an ee value of 92 %. © 2009 Wiley-VCH Verlag GmbH & Co. KCaA.

引用

页码：6640 / 6642

页数：3

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