Light-Driven Enantioselective Organocatalysis

被引:146
作者
Mueller, Christiane [1 ]
Bauer, Andreas [1 ]
Bach, Thorsten [1 ]
机构
[1] Tech Univ Munich, Lehrstuhl Organ Chem 1, D-85747 Garching, Germany
关键词
cycloadditions; enantioselectivity; organocatalysis; photochemistry; sensitizers; ASYMMETRIC CATALYSIS; MOLECULAR-OXYGEN; PHOTOCYCLOADDITION; CHIRALITY; CHEMISTRY;
D O I
10.1002/anie.200901603
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Collection, sensitization, and selection are the tasks of the organocatalyst 1, which it fulfills almost perfectly in the photochemical conversion of quinolone 2. It collects light (λ>350 nm), transfers its energy to the substrate, and induces a high enantioselectivity. Even with only 10 mol % of catalyst, a yield of 90 % was achieved with an ee value of 92 %. © 2009 Wiley-VCH Verlag GmbH & Co. KCaA.
引用
收藏
页码:6640 / 6642
页数:3
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