Asymmetric bioreduction of benzyl acetoacetate to its corresponding alcohol, benzyl (S)-(+)-3-hydroxybutyrate by the yeast Candida schatavii MY 1831

被引：7

作者：

Chartrain, M ^{[1
]}

McNamara, J ^{[1
]}

Greasham, R ^{[1
]}

机构：

[1] DEPT PROC RES,RAHWAY,NJ 07065

来源：

JOURNAL OF FERMENTATION AND BIOENGINEERING | 1996年 / 82卷 / 05期

关键词：

bioreduction; biocatalysis; asymmetric synthesis; bioprocess;

D O I：

10.1016/S0922-338X(97)86993-0

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The screening of 35 microbial strains yielded 13 of them as suitable biocatalysts for the asymmetric bioreduction of benzyl acetoacetate to its corresponding alcohol benzyl (S)-(+)-3-hydroxybutyrate. The production of benzyl (S)-(+)-3-hydroxybutyrate with an elevated optical purity of 93% was achieved when employing the yeast Candida schatavii strain MY 1831.

引用

页码：507 / 508

页数：2

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