Failure of elimination of paternal mitochondrial DNA in abnormal embryos

被引:73
作者
St John, J [1 ]
Sakkas, D
Dimitriadi, K
Barnes, A
Maclin, V
Ramey, J
Barratt, C
De Jonge, C
机构
[1] Birmingham Womens Hosp, Assisted Concept Unit, Birmingham B15 2TG, W Midlands, England
[2] Univ Nebraska, Med Ctr, Ctr Reprod Med, Omaha, NE USA
关键词
D O I
10.1016/S0140-6736(99)03842-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Paternal mitochondrial DNA is normally eliminated from mammalian embryos. We have shown the presence of paternal mtDNA at the blastocyst stage in some abnormal human embryos.
引用
收藏
页码:200 / 200
页数:1
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