HLA-B27, Cytokines, and Spondyloarthritis: Noncanonical Functions of a Curious Class I Major Histocompatibility Complex Gene

被引:3
作者
Gracey, Eric [1 ,2 ]
Haroon, Nigil [1 ,2 ]
Inman, Robert D. [1 ,2 ]
机构
[1] Univ Hlth Network, Toronto Western Res Inst, Toronto, ON, Canada
[2] Univ Toronto, Toronto, ON, Canada
关键词
ANKYLOSING-SPONDYLITIS; DENDRITIC CELLS; INFLAMMATORY DISEASE; T-CELLS; GUT; INTERLEUKIN-23; ASSOCIATION; MACROPHAGES; ACTIVATION; EXPRESSION;
D O I
10.1002/art.38316
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
[No abstract available]
引用
收藏
页码:783 / 785
页数:3
相关论文
共 22 条
[1]
Akram A., 2013, Eur. J. Immunol
[2]
Analysis of IL-17+ cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response [J].
Appel, Heiner ;
Maier, Rene ;
Wu, Peihua ;
Scheer, Rebecca ;
Hempfing, Axel ;
Kayser, Ralph ;
Thiel, Andreas ;
Radbruch, Andreas ;
Loddenkemper, Christoph ;
Sieper, Joachim .
ARTHRITIS RESEARCH & THERAPY, 2011, 13 (03)
[3]
Association of CD163+ macrophages and local production of soluble CD163 with decreased lymphocyte activation in spondylarthropathy synovitis [J].
Baeten, D ;
Moller, HJ ;
Delanghe, J ;
Veys, EM ;
Moestrup, SK ;
De Keyser, F .
ARTHRITIS AND RHEUMATISM, 2004, 50 (05) :1611-1623
[4]
BREWERTON DA, 1973, LANCET, V1, P904
[5]
Macrophage phenotype in the subclinical gut inflammation of patients with ankylosing spondylitis [J].
Ciccia, Francesco ;
Alessandro, Riccardo ;
Rizzo, Aroldo ;
Accardo-Palumbo, Antonina ;
Raimondo, Stefania ;
Raiata, Francesca ;
Guggino, Giuliana ;
Giardina, AnnaRita ;
De Leo, Giacomo ;
Sireci, Guido ;
Triolo, Giovanni .
RHEUMATOLOGY, 2014, 53 (01) :104-113
[6]
Cortes A, 2013, ARTHRITIS RHEUM-US, V65, pS723
[7]
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci [J].
Cortes, Adrian ;
Hadler, Johanna ;
Pointon, Jenny P. ;
Robinson, Philip C. ;
Karaderi, Tugce ;
Leo, Paul ;
Cremin, Katie ;
Pryce, Karena ;
Harris, Jessica ;
Lee, Seunghun ;
Joo, Kyung Bin ;
Shim, Seung-Cheol ;
Weisman, Michael ;
Ward, Michael ;
Zhou, Xiaodong ;
Garchon, Henri-Jean ;
Chiocchia, Gilles ;
Nossent, Johannes ;
Lie, Benedicte A. ;
Forre, Oystein ;
Tuomilehto, Jaakko ;
Laiho, Kari ;
Jiang, Lei ;
Liu, Yu ;
Wu, Xin ;
Bradbury, Linda A. ;
Elewaut, Dirk ;
Burgos-Vargas, Ruben ;
Stebbings, Simon ;
Appleton, Louise ;
Farrah, Claire ;
Lau, Jonathan ;
Kenna, Tony J. ;
Haroon, Nigil ;
Ferreira, Manuel A. ;
Yang, Jian ;
Mulero, Juan ;
Fernandez-Sueiro, Jose Luis ;
Gonzalez-Gay, Miguel A. ;
Lopez-Larrea, Carlos ;
Deloukas, Panos ;
Donnelly, Peter ;
Bowness, Paul ;
Gafney, Karl ;
Gaston, Hill ;
Gladman, Dafna D. ;
Rahman, Proton ;
Maksymowych, Walter P. ;
Xu, Huji ;
Crusius, J. Bart A. .
NATURE GENETICS, 2013, 45 (07) :730-+
[8]
HLA-B27 Misfolding and the Unfolded Protein Response Augment Interleukin-23 Production and Are Associated With Th17 Activation in Transgenic Rats [J].
Delay, Monica L. ;
Turner, Matthew J. ;
Klenk, Erin I. ;
Smith, Judith A. ;
Sowders, Dawn P. ;
Colbert, Robert A. .
ARTHRITIS AND RHEUMATISM, 2009, 60 (09) :2633-2643
[9]
Increased Body Mass Index in Ankylosing Spondylitis Is Associated with Greater Burden of Symptoms and Poor Perceptions of the Benefits of Exercise [J].
Durcan, Laura ;
Wilson, Fiona ;
Conway, Richard ;
Cunnane, Gaye ;
O'Shea, Finbar D. .
JOURNAL OF RHEUMATOLOGY, 2012, 39 (12) :2310-2314
[10]
Reverse Interferon Signature Is Characteristic of Antigen-Presenting Cells in Human and Rat Spondyloarthritis [J].
Fert, Ingrid ;
Cagnard, Nicolas ;
Glatigny, Simon ;
Letourneur, Franck ;
Jacques, Sebastien ;
Smith, Judith A. ;
Colbert, Robert A. ;
Taurog, Joel D. ;
Chiocchia, Gilles ;
Araujo, Luiza M. ;
Breban, Maxime .
ARTHRITIS & RHEUMATOLOGY, 2014, 66 (04) :841-851