Management of pneumococcal meningitis

被引：21

作者：

Kaplan, SL ^{[1
]}

机构：

[1] Texas Childrens Hosp, Houston, TX 77030 USA

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2002年 / 21卷 / 06期

关键词：

meningitis; pneumococcal; Streptococcus pneumoniae; management;

D O I：

10.1097/00006454-200206000-00034

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

During the past decade antibiotic resistance among Streptococcus pneumoniae isolates has complicated the empiric approach to and treatment of pneumococcal meningitis. Standard empiric therapy for suspected bacterial meningitis for infants and children older than 1 month of age is the combination of cefotaxime or ceftriaxone and vancomycin. Treatment is modified after antimicrobial susceptibilities are available. The optimal treatment of pneumococcal meningitis caused by strains with a cefotaxime/ceftriaxone MIC >2 mug/ml is unknown, although the addition of rifampin to the initial combination is generally recommended. The role of newer agents including quinolones is under investigation. Dexamethasone remains the only adjunctive antiinflammatory therapy to consider. The empiric approach to the child with suspected bacterial meningitis who has received the pneumococcal conjugate vaccine currently remains unchanged.

引用

收藏

页码：589 / 591

页数：3

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