Ganglioside GM3 and its biological functions

被引：74

作者：

Prokazova, N. V. ^{[1
]}

Samovilova, N. N. ^{[1
]}

Gracheva, E. V. ^{[1
]}

Golovanova, N. K. ^{[1
]}

机构：

[1] Russian Minist Hlth, Russian Cardiol Res Ctr, Inst Expt Cardiol, Moscow 121552, Russia

来源：

BIOCHEMISTRY-MOSCOW | 2009年 / 74卷 / 03期

基金：

俄罗斯基础研究基金会;

关键词：

ganglioside GM3; GM3; synthase; metabolism; cell differentiation; proliferation; oncogenesis; apoptosis; GROWTH-FACTOR RECEPTOR; MEMBRANE-ASSOCIATED SIALIDASE; N-ACETYLNEURAMINIC ACID; MELANOMA B16 CELLS; PROTEIN-KINASE-C; GLOMERULAR MESANGIAL CELLS; THIN-LAYER-CHROMATOGRAPHY; NECROSIS-FACTOR-ALPHA; BLADDER-CANCER CELLS; HL-60; CELLS;

D O I：

10.1134/S0006297909030018

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

Metabolism, topology, and possible mechanisms for regulation of the ganglioside GM3 content in the cell are reviewed. Under consideration are biological functions of GM3, such as involvement in cell differentiation, proliferation, oncogenesis, and apoptosis.

引用

页码：235 / 249

页数：15

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