Bronchiolitis obliterans organizing pneumonia in three children with acute leukaemias treated with cytosine arabinoside and anthracyclines

被引：24

作者：

Battistini, E ^{[1
]}

Dini, G ^{[1
]}

Savioli, C ^{[1
]}

Morando, A ^{[1
]}

Gandolfo, A ^{[1
]}

Kotitsa, Z ^{[1
]}

Garaventa, A ^{[1
]}

Rossi, GA ^{[1
]}

机构：

[1] IST GIANNINA GASLINI,SERV ANAT PATOL,I-16148 GENOA,ITALY

来源：

EUROPEAN RESPIRATORY JOURNAL | 1997年 / 10卷 / 05期

关键词：

anthracyclines; bronchiolitis obliterans organizing pneumonia; cytosine arabinoside; interstitial lung fibrosis; leukaemia;

D O I：

10.1183/09031936.97.10051187

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Bronchiolitis obliterans organizing pneumonia (BOOP) is a clinicopathological entity with well-defined diagnostic criteria, which can be idiopathic or produced by a variety of biological processes, We describe the occurrence of BOOP in three children, one with acute lymphoblastic leukaemia and two with acute promyelocytic leukaemia. In the three patients, BOOP developed 10-20 days after a course of therapy with cytosine arabinoside and anthracyclines. The possible relationships between the small conducting airway lesions, lung toxic reaction to the drugs and/or nonidentified infectious agents are discussed.

引用

页码：1187 / 1190

页数：4

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