Adenosine receptors as potential therapeutic targets

被引：56

作者：

Kaiser, SM ^{[1
]}

Quinn, RJ ^{[1
]}

机构：

[1] Griffith Univ, AstraZeneca R&D, Brisbane, Qld 4111, Australia

来源：

DRUG DISCOVERY TODAY | 1999年 / 4卷 / 12期

关键词：

D O I：

10.1016/S1359-6446(99)01421-X

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Recent studies indicate a widening role for adenosine receptors in many therapeutic areas. Adenosine receptors are involved in immunological and inflammatory responses, respiratory regulation, the cardiovascular system, the kidney, various CNS-mediated events including sleep and neuroprotection, as well as central and peripheral pain processes. In this review, the physiological role of adenosine receptors In these key areas is described with reference to the therapeutic potential of adenosine receptor agonists and antagonists.

引用

页码：542 / 551

页数：10

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