Neuropsychiatric outcomes of stroke

被引：77

作者：

Hackett, Maree L. ^{[1
,2
]}

Kohler, Sebastian ^{[3
]}

O'Brien, John T. ^{[4
,5
]}

Mead, Gillian E. ^{[6
]}

机构：

[1] Univ Sydney, George Inst Global Hlth, Sydney, NSW 2006, Australia

[2] Univ Cent Lancashire, Preston PR1 2HE, Lancs, England

[3] Maastricht Univ, Sch Mental Hlth & Neurosci, Alzheimer Ctr Limburg, Maastricht, Netherlands

[4] Univ Cambridge, Dept Psychiat, Cambridge, England

[5] Cambridgeshire & Peterborough NHS Fdn Trust, Cambridge, England

[6] Royal Infirm, Edinburgh EH16 4SA, Midlothian, Scotland

来源：

LANCET NEUROLOGY | 2014年 / 13卷 / 05期

基金：

英国医学研究理事会;

关键词：

POSTSTROKE DEPRESSION; EMOTIONAL INCONTINENCE; NATURAL-HISTORY; ISCHEMIC-STROKE; PSYCHOLOGICAL SYMPTOMS; SCREENING INSTRUMENTS; MAJOR DEPRESSION; LESION LOCATION; FATIGUE; APATHY;

D O I：

10.1016/s1474-4422(14)70016-X

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

The most common neuropsychiatric outcomes of stroke are depression, anxiety, fatigue, and apathy, which each occur in at least 30% of patients and have substantial overlap of prevalence and symptoms. Emotional lability, personality changes, psychosis, and mania are less common but equally distressing symptoms that are also challenging to manage. The cause of these syndromes is not known, and there is no dear relation to location of brain lesion. There are important gaps in knowledge about how to manage these disorders, even for depression, which is the most studied syndrome. Further research is needed to identify causes and interventions to prevent and treat these disorders.

引用

页码：525 / 534

页数：10

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