Differences in rate and variability of intracellular growth of a panel of Mycobacterium tuberculosis clinical isolates within a human monocyte model

被引：70

作者：

Li, Q

Whalen, CC

Albert, JM

Larkin, R

Zukowski, L

Cave, MD

Silver, RF

机构：

[1] Case Western Reserve Univ, Sch Med, Dept Med, Div Pulm & Crit Care Med, Cleveland, OH 44106 USA

[2] Case Western Reserve Univ, Sch Med, Dept Epidemiol & Biostat, Cleveland, OH 44106 USA

[3] Univ Hosp Cleveland, Cleveland, OH 44106 USA

[4] Univ Arkansas Med Sci, Little Rock, AR 72205 USA

来源：

INFECTION AND IMMUNITY | 2002年 / 70卷 / 11期

关键词：

D O I：

10.1128/IAI.70.11.6489-6493.2002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Significant differences were observed in the capacities of Mycobacterium tuberculosis clinical isolates to grow within human monocytes. Genotyping indicated that the four most rapidly growing isolates were members of the Beijing strain family. M. tuberculosis strain H37Rv provided more reproducible infection than the clinical isolates or M. tuberculosis Erdman.

引用

收藏

页码：6489 / 6493

页数：5

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