Alcohol use, physical performance, and functional limitations in older men

被引:46
作者
Cawthon, Peggy M.
Fink, Howard A.
Barrett-Connor, Elizabeth
Cauley, Jane A.
Dam, Thuy-Tien
Lewis, Cora E.
Marshall, Lynn M.
Orwoll, Eric S.
Cummings, Steven R.
机构
[1] Calif Pacific Med Ctr, Res Inst, San Francisco, CA 94115 USA
[2] VA Med Ctr, Geriatr Res Educ & Clni Ctr, Ctr Chron Dis Outcomes Res, Minneapolis, MN USA
[3] VA Med Ctr, Dept Med, Minneapolis, MN USA
[4] Univ Calif San Diego, Sch Med, Dept Family & Prevent Med, La Jolla, CA 92093 USA
[5] Univ Pittsburgh, Dept Epidemiol, Pittsburgh, PA 15260 USA
[6] Univ Alabama, Birmingham, AL 35233 USA
[7] Oregon Hlth Sci Univ, Dept Med, Portland, OR 97201 USA
关键词
alcohol; instrumental activities of daily living (IADL); functional status; CAGE; physical performance;
D O I
10.1111/j.1532-5415.2007.01062.x
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
OBJECTIVES: To describe associations between recent alcohol intake, physical performance, and functional limitations in older men. DESIGN: Cross-sectional study. SETTING: Six U.S. clinical centers. PARTICIPANTS: Five thousand nine hundred sixty-two men aged 65 and older. MEASUREMENTS: Self-reported functional limitations; problem drinking history (>= 2 positive responses on the CAGE questionnaire); history of sustained excessive drinking (history of consumption of >= 5 drinks/day on most days); and alcohol intake categorized by drinks/week (0=abstainers, n=2,116; < 1=intermittent, n=739); 1 to < 7= light, n=1,563; 7 to < 14=low-moderate, n=848; 14 to < 21 =high-moderate, n=459; and >= 21=heavy, n=237). Grip strength, leg power, chair stand, and walking tests were completed during a standard examination. RESULTS: After age adjustment, men with low-moderate or high-moderate intake generally performed 3% to 5% better on physical performance tests than abstainers; heavy drinkers performed similarly to abstainers. These associations lessened yet tended to remain significant after multivariate adjustment. Men with low-moderate alcohol intake had the lowest odds of reporting a limitation in instrumental activities of daily living (multivariate-adjusted odds ratio (OR)=0.52, 95% confidence interval (CI)=0.39-0.69) compared to abstainers; similar odds were seen for high-moderate and heavy use. The association between alcohol intake and self-reported physical limitation was U-shaped, with the highest odds of physical limitation in abstainers (OR=1.0, referent) and heavy users (OR=0.88, 95% CI=0.58-1.36) and the lowest odds in low-moderate users (OR=0.62, 95% CI=0.46-0.95). CONCLUSION: Moderate alcohol intake was associated with modestly better physical performance and lower odds of reporting a functional limitation in older men.
引用
收藏
页码:212 / 220
页数:9
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