Functional magnetic resonance imaging shows localized brain activation during serial transcranial stimulation in man

被引：21

作者：

Brandt, SA ^{[1
]}

Davis, TL ^{[1
]}

Obrig, H ^{[1
]}

Meyer, BU ^{[1
]}

Belliveau, JW ^{[1
]}

Rosen, BR ^{[1
]}

Villringer, A ^{[1
]}

机构：

[1] MASSACHUSETTS GEN HOSP,DEPT RADIOL,BOSTON,MA

来源：

NEUROREPORT | 1996年 / 7卷 / 03期

关键词：

fMRI; brain activation; transcranial stimulation; cerebral blood flow; deoxyhaemoglobin; motor cortex;

D O I：

10.1097/00001756-199602290-00013

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

AREA and depth penetration of transcranial stimulation methods such as transcranial electrical stimulation (TES) are poorly defined. We investigated the feasibility of a simultaneous TES and fMRI measurement. The aim was to compare the signal intensity changes measured using BOLD fMRI during sequential finger movement with the signal response during artificial transcranial stimulation. TES induced contralateral finger contractions and in T2* weighted images a transient signal increase was observed in the area underlying the electrodes. Compared with the signal obtained during sequential finger movements, the area activated by TES was more localized, signal amplitude was smaller and there was no poststimulus undershoot. These data indicate that TES induces a local blood flow increase associated with a drop in the concentration of deoxyhaemoglobin.

引用

页码：734 / 736

页数：3

共 6 条

[1]

Cadwell J, 1990, MAGNETIC STIMULATION, P13

[2] CONGENITAL MIRROR MOVEMENTS - ABNORMAL ORGANIZATION OF MOTOR PATHWAYS IN 2 PATIENTS [J].

COHEN, LG ;

MEER, J ;

TARKKA, I ;

BIERNER, S ;

LEIDERMAN, DB ;

DUBINSKY, RM ;

SANES, JN ;

JABBARI, B ;

BRANSCUM, B ;

HALLETT, M .

BRAIN, 1991, 114 :381-403

[3] Simultaneous functional magnetic resonance imaging and electrophysiological recording [J].

HuangHellinger, FR ;

Breiter, HC ;

McCormack, G ;

Cohen, MS ;

Kwong, KK ;

Sutton, JP ;

Savoy, RL ;

Weisskoff, RM ;

Davis, TL ;

Baker, JR ;

Belliveau, JW ;

Rosen, BR .

HUMAN BRAIN MAPPING, 1995, 3 (01) :13-23

[4] DYNAMIC MAGNETIC-RESONANCE-IMAGING OF HUMAN BRAIN ACTIVITY DURING PRIMARY SENSORY STIMULATION [J].

KWONG, KK ;

BELLIVEAU, JW ;

CHESLER, DA ;

GOLDBERG, IE ;

WEISSKOFF, RM ;

PONCELET, BP ;

KENNEDY, DN ;

HOPPEL, BE ;

COHEN, MS ;

TURNER, R ;

CHENG, HM ;

BRADY, TJ ;

ROSEN, BR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (12) :5675-5679

[5] INHIBITORY AND EXCITATORY INTERHEMISPHERIC TRANSFERS BETWEEN MOTOR CORTICAL AREAS IN NORMAL HUMANS AND PATIENTS WITH ABNORMALITIES OF THE CORPUS-CALLOSUM [J].

MEYER, BU ;

RORICHT, S ;

VONEINSIEDEL, HG ;

KRUGGEL, F ;

WEINDL, A .

BRAIN, 1995, 118 :429-440

[6] THE EFFECT OF MAGNETIC COIL ORIENTATION ON THE LATENCY OF SURFACE EMG AND SINGLE MOTOR UNIT RESPONSES IN THE FIRST DORSAL INTEROSSEOUS MUSCLE [J].

WERHAHN, KJ ;

FONG, JKY ;

MEYER, BU ;

PRIORI, A ;

ROTHWELL, JC ;

DAY, BL ;

THOMPSON, PD .

ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1994, 93 (02) :138-146

← 1 →