Determination of natural versus laboratory human infection with Mayaro virus by molecular analysis

被引：14

作者：

Junt, T ^{[1
]}

Heraud, JM ^{[1
]}

Lelarge, J ^{[1
]}

Labeau, B ^{[1
]}

Talarmin, A ^{[1
]}

机构：

[1] Inst Pasteur, Ctr Nacl Reference Surveillance Arboviroses Reg A, Cayenne 97306, French Guiana

来源：

EPIDEMIOLOGY AND INFECTION | 1999年 / 123卷 / 03期

关键词：

D O I：

10.1017/S0950268899003180

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A laboratory worker developed clinical signs of infection with Mayaro virus (Togaviridae), an arbovirus of South and Central America, 6 days after preparation of Mayaro viral antigen and 10 days after a trip to a rain forest. There was no evidence of skin lesions during the antigen preparation, and level 3 containment safety measures were followed. Therefore, molecular characterization of the virus was undertaken to identify the source of infection. RT-PCR and DNA sequence comparisons proved the infection was with the laboratory strain. Airborne Mayaro virus contamination is thus a hazard to laboratory personnel.

引用

页码：511 / 513

页数：3

共 9 条

[1] MAYARO VIRUS - A NEW HUMAN DISEASE AGENT .2. ISOLATION FROM BLOOD OF PATIENTS IN TRINIDAD, BWI [J].

ANDERSON, CR ;

DOWNS, WG ;

WATTLEY, GH ;

AHIN, NW ;

REESE, AA .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1957, 6 (06) :1012-1016

[2]

FRANCKI RIB, 1991, ARCH VIROL S, V2, P216

[3] ARBOVIRUS INFECTIONS OF LABORATORY WORKERS - EXTENT OF PROBLEM EMPHASIZES NEED FOR MORE EFFECTIVE MEASURES TO REDUCE HAZARDS [J].

HANSON, RP ;

SULKIN, SE ;

BUESCHER, EL ;

HAMMON, WM ;

MCKINNEY, RW ;

WORK, TH .

SCIENCE, 1967, 158 (3806) :1283-+

[4] A simple device for the exposure of animals to infectious microorganisms by the airborne route [J].

Phillpotts, RJ ;

Brooks, TJG ;

Cox, CS .

EPIDEMIOLOGY AND INFECTION, 1997, 118 (01) :71-75

[5]

Pinheiro F. P., 1988, The arboviruses: epidemiology and ecology. Volume III., P137

[6] AN OUTBREAK OF MAYARO VIRUS-DISEASE IN BELTERRA, BRAZIL .1. CLINICAL AND VIROLOGICAL FINDINGS [J].

PINHEIRO, FP ;

FREITAS, RB ;

DAROSA, JFT ;

GABBAY, YB ;

MELLO, WA ;

LEDUC, JW .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1981, 30 (03) :674-681

[7]

SCHERER WF, 1980, AM J TROP MED HYG, V29, P1359

[8]

SERGEEV AN, 1991, VOP VIRUSOL+, V36, P492

[9] Mayaro virus fever in French Guiana:: Isolation, identification, and seroprevalence [J].

Talarmin, A ;

Chandler, LJ ;

Kazanji, M ;

De Thoisy, B ;

Debon, P ;

Lelarge, J ;

Labeau, B ;

Bourreau, E ;

Vié, JC ;

Shope, RE ;

Sarthou, JL .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1998, 59 (03) :452-456

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