Solid-phase synthesis of substituted alkynes using the Nicholas reaction

被引：20

作者：

Cassel, JA ^{[1
]}

Leue, S ^{[1
]}

Gachkova, NI ^{[1
]}

Kann, NC ^{[1
]}

机构：

[1] Chalmers Univ Technol, Dept Organ Chem, SE-41296 Gothenburg, Sweden

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 26期

关键词：

D O I：

10.1021/jo026156u

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first example of a Nicholas reaction on solid phase is reported, involving the reaction of cobalt complexes of polymer-bound alkynols with different nucleophiles in the presence of a Lewis acid, to form carbon-oxygen or carbon-carbon bonds.

引用

页码：9460 / 9463

页数：4

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