Keratinocyte junctions and the epidermal barrier: how to make a skin-tight dress

被引:20
作者
Bazzoni, G
Dejana, E
机构
[1] FIRC Inst Mol Oncol, I-20139 Milan, Italy
[2] Ist Ric Farmacol Mario Negri, I-20157 Milan, Italy
关键词
D O I
10.1083/jcb.200202116
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Although intercellular junctions are known to be the major regulators of permeability of simple epithelia, they had not been thought to be important in regulating the permeability of stratified mammalian epithelia. Furuse et al. (2002, this issue) demonstrate that functional tight junctions may indeed be a necessary part of the permeability barrier of the skin.
引用
收藏
页码:947 / 949
页数:3
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