The role of inflammatory cytokines in Meigs' syndrome

被引：56

作者：

Abramov, Y ^{[1
]}

Anteby, SO

Fasouliotis, SJ

Barak, V

机构：

[1] Hebrew Univ Jerusalem, Hadassah Med Ctr, Dept Obstet & Gynecol, IL-91120 Jerusalem, Israel

[2] Hebrew Univ Jerusalem, Hadassah Med Ctr, Immunol Lab Tumor Diag, IL-91120 Jerusalem, Israel

[3] Hebrew Univ Jerusalem, Hadassah Med Ctr, Israeli Cytokine Standardizat Lab, IL-91120 Jerusalem, Israel

来源：

OBSTETRICS AND GYNECOLOGY | 2002年 / 99卷 / 05期

关键词：

D O I：

10.1016/S0029-7844(01)01602-7

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

BACKGROUND: Inflammatory cytokines are known to induce capillary leakage and third-space fluid accumulation in numerous gynecologic and nongynecologic disorders. This study aimed to assess their role in Meigs' syndrome. CASE: Evaluation of serum, peritoneal, and pleural fluids retrieved from a patient suffering from Meigs' syndrome revealed high interleukin (IL)-1beta IL-6, IL-8, and tumor necrosis factor (TNF)-alpha levels. After surgical removal of the ovarian tumor and with resolution of ascites and hydrothorax, serum levels of IL-1beta, 1L-6, and IL-8 declined,.vhereas tumor necrosis factor-alpha levels remained high. CONCLUSION: The correlation between these inflammatory cytokines and the clinical course of Meigs' syndrome suggests their involvement in the formation of ascites and hydrothorax in this disorder. (C) 2002 by the American College of Obstetricians and Gynecologists.

引用

页码：917 / 919

页数：3

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