Targeting the subthalamic nucleus

被引:35
作者
Aziz, TZ
Nandi, D
Parkin, S
Liu, X
Giladi, N
Bain, P
Gregory, RG
Joint, C
Scott, RB
Stein, JF
机构
[1] Univ Oxford, Radcliffe Infirm, Physiol Lab, Oxford OX2 6HE, England
[2] Radcliffe Infirm, Dept Neurosurg, Oxford OX2 6HE, England
[3] Radcliffe Infirm, Dept Neurol, Oxford OX2 6HE, England
[4] Charing Cross Hosp, Dept Neurol, London, England
关键词
subthalamic nucleus; targeting; lesions; stimulation; Parkinson's disease;
D O I
10.1159/000064602
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The small size and surrounding neuronal structures and fibre tracts make the STN a difficult stereotactic target. In this article we present the technique used by us to target the STN. Our combined experience from two centres comprises 18 lesions and 27 stimulator implants in the STN. Our criteria for patient selection and the use of MRI, frame-on CT and volumetric image fusion are presented. The role of a movement disorder specialist neurologist in the operating theatre, local field potential recording, impedance monitoring, macrostimulation, post-operative CT/MRI and test stimulation are detailed. Copyright (C) 2002 S. KargerAG, Basel.
引用
收藏
页码:87 / 90
页数:4
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