DNA damage: Air-breaks?

被引：24

作者：

Barnes, DE ^{[1
]}

机构：

[1] Canc Res UK London Res Inst, Clare Hall Labs, S Mimms EN6 3LD, Herts, England

来源：

CURRENT BIOLOGY | 2002年 / 12卷 / 07期

关键词：

D O I：

10.1016/S0960-9822(02)00788-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cells deficient in repairing DNA double-strand breaks have an increased level of spontaneous chromosomal aberrations. Modulating the level of molecular oxygen and its reactive metabolites demonstrates that oxygen metabolism is a major source of genomic instability.

引用

页码：R262 / R264

页数：3

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