Two new 15-deoxycimigenol-type and three new 24-epi-cimigenol-type glycosides from Cimicifuga Rhizome

被引:18
作者
Yoshimitsu, Hitoshi
Nishida, Makiko
Sakaguchi, Masahide
Nohara, Toshihiro
机构
[1] Sojo Univ, Fac Pharmaceut Sci, Kumamoto 8620082, Japan
[2] Kyushu Kyoritsu Univ, Fac Engn, Yahatanishi Ku, Kitakyushu, Fukuoka 8078585, Japan
[3] Kumamoto Univ, Fac Med & Pharmaceut Sci, Kumamoto 8620973, Japan
关键词
Cimicifuga Rhizome; cycloartane glycoside; Cimicifuga sp; Ranunculaceae;
D O I
10.1248/cpb.54.1322
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Two new 15-deoxycimigenol-type (1, 2) and three new 24-epi-cimigenol-type glycosides (3-5) were isolated from Cimicifuga Rhizome, and the structures were elucidated on the basis of spectroscopic data including 2D NMR spectra and chemical evidence. The two new 15-deoxycimigenol-type glycosides were the first cimigenol-type glycosides lacking a hydroxyl group at C-15.
引用
收藏
页码:1322 / 1325
页数:4
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