A calcium-dependent nitric oxide synthase and NMDA R1 glutamate receptor in the ink gland of Sepia officinalis: A hint to a regulatory role of nitric oxide in melanogenesis?

被引：33

作者：

Palumbo, A

DiCosmo, A

Gesualdo, I

dIschia, M

机构：

[1] UNIV NAPLES FEDERICO II, DEPT ZOOL, NAPLES, ITALY

[2] UNIV NAPLES FEDERICO II, DEPT ORGAN & BIOL CHEM, NAPLES, ITALY

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1997年 / 235卷 / 02期

关键词：

D O I：

10.1006/bbrc.1997.6734

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Histochemical, immunohistochemical, and biochemical evidence is reported showing that the ink gland of the cuttlefish Sepia officinalis contains a calcium-dependent isoform of nitric oxide synthase as well as an NMDA R1 receptor subunit localized for the most part in the immature inner cells of the epithelial layer of the gland. These results may be taken to implicate a hitherto unrecognized regulatory role of the glutamate-nitric oxide pathway in the maturation and metabolic activity of melanin-producing cells in the cephalopod defense system. (C) 1997 Academic Press.

引用

页码：429 / 432

页数：4

共 18 条

[1] Constitutive nitric oxide synthase is present in normal human keratinocytes [J].