Molecular cloning of rabbit CARP cDNA and its regulated expression in adriamycin-cardiomyopathy

被引：11

作者：

Aihara, Y

Kurabayashi, M

Arai, M

Kedes, L

Nagai, R

机构：

[1] Gunma Univ, Sch Med, Dept Internal Med 2, Maebashi, Gumma 3718511, Japan

[2] Univ So Calif, Sch Med, Inst Med Genet, Los Angeles, CA 90033 USA

[3] Univ So Calif, Sch Med, Dept Biochem & Mol Biol, Los Angeles, CA 90033 USA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1999年 / 1447卷 / 2-3期

关键词：

cardiac adriamycin responsive protein; adriamycin-cardiomyopathy; SERCA2;

D O I：

10.1016/S0167-4781(99)00171-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A full-length rabbit cDNA of cardiac adriamycin responsive protein (CARP) has been cloned. It shows high levels of identity at the amino acid sequence level (> 86%) with the rat, mouse and human homologues. CARP mRNA levels are highly regulated in adriamycin-cardiomyopathy in rabbits. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：318 / 324

页数：7

共 31 条

[1] Sarcoplasmic reticulum genes are selectively down-regulated in cardiomyopathy produced by doxorubicin in rabbits [J].