Articular cartilage tissue engineering TODAY'S RESEARCH, TOMORROW'S PRACTICE?

被引:123
作者
Getgood, A. [1 ]
Brooks, R. [1 ]
Fortier, L. [1 ]
Rushton, N. [1 ]
机构
[1] Univ Cambridge, Orthopaed Res Unit, Cambridge CB2 2QQ, England
来源
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME | 2009年 / 91B卷 / 05期
关键词
MESENCHYMAL STEM-CELLS; AUTOLOGOUS CHONDROCYTE IMPLANTATION; FIBROBLAST-GROWTH-FACTOR; PLATELET-RICH PLASMA; OSTEOCHONDRAL DEFECTS; TRANSFORMING GROWTH-FACTOR-BETA-1; IN-VIVO; ENHANCED REPAIR; FACTOR-BETA; STIMULATES CHONDROGENESIS;
D O I
10.1302/0301-620X.91B5.21832
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
100224 [整形外科学];
摘要
Articular cartilage repair remains a challenge to surgeons and basic scientists. The field of tissue engineering allows the simultaneous use of material scaffolds, cells and signalling molecules to attempt to modulate the regenerative tissue. This review summarises the research that has been undertaken to date using this approach, with a particular emphasis on those techniques that have been introduced into clinical practice, via in vitro and preclinical studies.
引用
收藏
页码:565 / 576
页数:12
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