Triterpenoid Saponins from Dianthus versicolor

被引：37

作者：

Ma, Li ^{[1
]}

Gu, Yu-Cheng ^{[2
]}

Luo, Jian-Guang ^{[1
]}

Wang, Jun-Song ^{[1
]}

Huang, Xue-Feng ^{[1
]}

Kong, Ling-Yi ^{[1
]}

机构：

[1] China Pharmaceut Univ, Dept Nat Med Chem, Nanjing 210009, Peoples R China

[2] Syngenta, Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England

来源：

JOURNAL OF NATURAL PRODUCTS | 2009年 / 72卷 / 04期

基金：

中国国家自然科学基金;

关键词：

ORIENTAL MEDICINES; VALIDITY; CONSTITUENTS;

D O I：

10.1021/np800589a

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Seven new pentacyclic triterpenoid saponins, named dianversicosides A-G (1-7), together with nine known compounds, were isolated from the aerial parts of Dianthus versicolor. The structures of 1-7 were elucidated on the basis of spectroscopic data and chemical evidence. The absolute configuration of the 3-hydroxyl-3-methylglutaryl (HMG) group in 1-4 was ascertained by chemical analysis combined with a chiral HPLC method. Cytotoxic activities of the isolated compounds were evaluated against a small panel of cancer and other cell lines.

引用

页码：640 / 644

页数：5

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