IN VITRO GENOTOXICITY OF SETTAT TOWN LANDFILL LEACHATE, MOROCCO

被引：14

作者：

Amahdar, Loubna ^{[1
]}

Anouar, Abdellah ^{[1
]}

Ababou, Bouchra ^{[1
]}

Verschaeve, Luc ^{[2
]}

Hilali, Abderraouf ^{[1
]}

机构：

[1] Univ Hassan 1, Fac Sci & Technol, Agrofood & Hlth Lab, Settat 26000, Morocco

[2] Sci Inst Publ Hlth, Toxicol Lab, Brussels, Belgium

来源：

ARHIV ZA HIGIJENU RADA I TOKSIKOLOGIJU-ARCHIVES OF INDUSTRIAL HYGIENE AND TOXICOLOGY | 2009年 / 60卷 / 02期

关键词：

dose-effect; lymphocyte; micronucleus; physico-chemical properties; proliferation index; toxicity; MUTAGENIC-ACTIVITY; SOLID-WASTE; ROOT-TIPS; MICRONUCLEUS; ASSAY; TOXICITY; CELLS; WATER;

D O I：

10.2478/10004-1254-60-2009-1925

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

100235 [预防医学];

摘要：

With the increasing use of landfill sites, leachates produced by uncontrolled waste disposal have became a serious threat for the aquatic environment. The aim of this study was to evaluate the genotoxicity of leachate and of well water sampled close to the town of Settat in Morocco using the micronucleus test and proliferation kinetics of human peripheral blood lymphocytes in vitro. We also analysed a number of physical and chemical parameters, including pH, % O-2, chemical oxygen demand (COD), HCO3-, Ca2+, Mg2+, Cl-, and conductivity. The analysis showed much higher levels of nearly all parameters than the Moroccan standard. Increased micronucleus frequencies were also found for both leachate and well water. Preliminary results indicate that both types of water are genotoxic and pose environmental and human health risk.

引用

页码：179 / 184

页数：6

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