Incidental Magnetic Resonance Diffusion-Weighted Imaging-Positive Lesions Are Rare in Neurologically Asymptomatic Community-Dwelling Adults

被引：27

作者：

Batool, Saima ^{[1
]}

O'Donnell, Martin ^{[2
,3
]}

Sharma, Mukul ^{[2
,3
]}

Islam, Shofiqul ^{[2
,3
]}

Dagenais, Gilles R. ^{[4
]}

Poirier, Paul ^{[4
]}

Lear, Scott A. ^{[5
,6
]}

Wielgosz, Andreas ^{[7
,8
]}

Teo, Koon ^{[2
,3
]}

Stotts, Grant ^{[7
,8
]}

McCreary, Cheryl R. ^{[9
,10
]}

Frayne, Richard ^{[1
,9
,10
,11
]}

DeJesus, Jane ^{[2
,3
]}

Rangarajan, Sumathy ^{[2
,3
]}

Yusuf, Salim ^{[2
,3
]}

Smith, Eric E. ^{[1
,9
,10
,11
]}

机构：

[1] Univ Calgary, Dept Clin Neurosci, Calgary, AB, Canada

[2] McMaster Univ, Dept Med, Populat Hlth Res Inst, Hamilton, ON, Canada

[3] Hamilton Hlth Sci, Hamilton, ON, Canada

[4] Univ Laval, Quebec Heart & Lung Inst, Quebec City, PQ, Canada

[5] Simon Fraser Univ, Fac Hlth Sci, Burnaby, BC V5A 1S6, Canada

[6] Providence Hlth Care, Div Cardiol, Vancouver, BC, Canada

[7] Ottawa Hosp, Ottawa, ON, Canada

[8] Univ Ottawa, Ottawa, ON, Canada

[9] Univ Calgary, Dept Radiol, Calgary, AB, Canada

[10] Alberta Hlth Serv, Seaman Family MR Res Ctr, Calgary, AB, Canada

[11] Univ Calgary, Hotchkiss Brain Inst, Calgary, AB, Canada

来源：

STROKE | 2014年 / 45卷 / 07期

基金：

加拿大健康研究院;

关键词：

magnetic resonance imaging; stroke; MICROINFARCTS; INFARCTS; BURDEN; SILENT;

D O I：

10.1161/STROKEAHA.114.005782

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background and Purpose-Incidental magnetic resonance diffusion-weighted imaging (DWI)-positive lesions, considered to represent small acute infarcts, have been detected in patients with cerebral small vessel diseases or cognitive impairment, but the prevalence in the community population is unknown. Methods-DWI sequences collected in 793 participants in the Prospective Urban Rural Epidemiological (PURE) study were reviewed for DWI lesions consistent with small acute infarcts. Results-No DWI-positive lesions were detected (0%, 95% confidence interval, 0-0.5). Conclusions-DWI-positive lesions are rare in an asymptomatic community population. The prevalence of DWI-positive lesions in the community seems to be lower than in patients with cerebral amyloid angiopathy, intracerebral hemorrhage, or cognitive impairment.

引用

页码：2115 / 2117

页数：3

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