Inhibition of low density lipoprotein oxidation by tetrahydrofurofuran lignans from Forsythia suspensa and Magnolia coco

被引：55

作者：

Chen, CC

Chen, HY

Shiao, MS

Lin, YL

Kuo, YH

Ou, JC

机构：

[1] Natl Res Inst Chinese Med, Taipei 112, Taiwan

[2] Natl Yang Ming Univ, Sch Med, Inst Tradit Med, Taipei 112, Taiwan

[3] Vet Gen Hosp, Dept Med Res & Educ, Taipei, Taiwan

[4] Natl Taiwan Univ, Dept Chem, Taipei 10764, Taiwan

来源：

PLANTA MEDICA | 1999年 / 65卷 / 08期

关键词：

Forsythia suspense (Thunb.) Vahl; Oleaceae; Magnolia coco (Lour.) DC; Magnoliaceae; antioxidants; pinoresinol; phillygenin; syringaresinol;

D O I：

10.1055/s-1999-14093

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Based on the inhibition of Cu2+-induced LDL oxidation as marker, the major antioxidants in the fruits Of Forsythia suspense and the stems of Magnolia coco were identified. Of these bioactive tetrahydrofurofuran lignans, pinoresinol, phillygenin, and syringaresinol were more potent than probucol. Sesamin and fargesin, which do not contain phenol groups, were found much less active.

引用

页码：709 / 711

页数：3

共 17 条

[1] LIRIORESINOL-C DIMETHYL ETHER A DIAXIALLY SUBSTITUTED 3,7-DIOXABICYCLO[3,3,0]OCTANE LIGNAN FROM MACROPIPER EXCELSUM (FORST F) MIQ [J].