Immune reconstitution hepatitis in HIV and hepatitis B coinfection, despite lamivudine therapy as part of HAART

被引：57

作者：

Drake, A

Mijch, A

Sasadeusz, J

机构：

[1] Alfred Hosp, Melbourne, Vic, Australia

[2] Royal Melbourne Hosp, Melbourne, Vic, Australia

来源：

CLINICAL INFECTIOUS DISEASES | 2004年 / 39卷 / 01期

关键词：

D O I：

10.1086/421386

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) coinfection occurs commonly. The introduction of antiretroviral therapy can result in immune reconstitution hepatitis. We describe 2 coinfected patients who developed clinical flares of HBV disease, despite the inclusion of lamivudine, a drug with anti-HBV activity, in their HAART regimens. Potential strategies to manage individuals with HBV/HIV coinfection are discussed.

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页码：129 / 132

页数：4

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