The Myelodysplastic Syndromes

被引：21

作者：

Nguyen, Phuong L. ^{[1
]}

机构：

[1] Mayo Clin, Div Hematopathol, Dept Lab Med & Pathol, Rochester, MN 55905 USA

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2009年 / 23卷 / 04期

关键词：

Myelodysplastic syndromes; Refractory anemia; Refractory cytopenia; Ineffective hematopoiesis; Bone marrow failure; BONE-MARROW; LOW-RISK; CHROMOSOMAL LESIONS; UNIPARENTAL DISOMY; REFRACTORY-ANEMIA; DARBEPOETIN-ALPHA; MYELOID-LEUKEMIA; SCORING SYSTEM; MDS; METHYLATION;

D O I：

10.1016/j.hoc.2009.04.008

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Myelodysplastic syndromes (MDS) are a heterogeneous group of bone marrow disorders that affect mostly the elderly and have a variable probability of progression to acute leukemia. The diagnosis of MDS rests largely on a critical morphologic review of blood and bone marrow slides, with careful correlation with other clinical and essential laboratory data, including cytogenetics. This article discusses the epidemiology and clinical and pathologic features of MDS and pertinent diagnostic and prognostic classifications, with a brief overview of treatment options. Other considerations in the differential diagnosis are also briefly outlined.

引用

页码：675 / +

页数：18

共 50 条

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