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Structure-activity relationships for In vitro and In vivo toxicity
被引:68
作者
:
Blagg, Julian
论文数:
0
引用数:
0
h-index:
0
机构:
Pfizer Global Res & Dev, Sandwich CT13 9NJ, Kent, England
Pfizer Global Res & Dev, Sandwich CT13 9NJ, Kent, England
Blagg, Julian
[
1
]
机构
:
[1]
Pfizer Global Res & Dev, Sandwich CT13 9NJ, Kent, England
来源
:
ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 41
|
2006年
/ 41卷
关键词
:
D O I
:
10.1016/S0065-7743(06)41024-1
中图分类号
:
R914 [药物化学];
学科分类号
:
100701 ;
摘要
:
[No abstract available]
引用
收藏
页码:353 / 368
页数:16
相关论文
共 85 条
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Anders MW, 2001, ADV EXP MED BIOL, V500, P113
[2]
Skin sensitization: Reaction mechanistic applicability domains for structure-activity relationships
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0
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Unilever Res Labs Colworth, SEAC, Sharnbrook MK44 1LQ, Beds, England
Roberts, DW
[J].
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: 1420
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[3]
Carcinogenicity of the aromatic amines: From structure-activity relationships to mechanisms of action and risk assessment
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Ist Super Sanita, Comparat Toxicol & Ecotoxicol Lab, I-00161 Rome, Italy
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Benigni, R
Passerini, L
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Ist Super Sanita, Comparat Toxicol & Ecotoxicol Lab, I-00161 Rome, Italy
Ist Super Sanita, Comparat Toxicol & Ecotoxicol Lab, I-00161 Rome, Italy
Passerini, L
[J].
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH,
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511
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: 191
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[4]
Toxicity testing: creating a revolution based on new technologies
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[J].
TRENDS IN BIOTECHNOLOGY,
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: 299
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[5]
Quinoids, quinoid radicals, and phenoxyl radicals formed from estrogens and antiestrogens
Bolton, JL
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0
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Univ Illinois, Coll Pharm, Dept Med Chem & Pharmacognosy, Chicago, IL 60612 USA
Univ Illinois, Coll Pharm, Dept Med Chem & Pharmacognosy, Chicago, IL 60612 USA
Bolton, JL
[J].
TOXICOLOGY,
2002,
177
(01)
: 55
-
65
[6]
BOSWELLSMITH V, 2005, CURR OPIN INV DRUGS, V6, P1136
[7]
Early prediction of drug metabolism and toxicity: systems biology approach and modeling
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GeneCo, St Joseph, MI 49085 USA
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GeneCo, St Joseph, MI 49085 USA
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Nikolsky, Y
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Nikolsky, Y
[J].
DRUG DISCOVERY TODAY,
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: 127
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[8]
Comparison of the computer programs DEREK and TOPKAT to predict bacterial mutagenicity
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Wilson, JD
Britt, BH
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0
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GlaxoSmithKline Inc, Safety Assessment, Res Triangle Pk, NC 27709 USA
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GlaxoSmithKline Inc, Safety Assessment, Res Triangle Pk, NC 27709 USA
Gombar, V
[J].
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17
(04)
: 321
-
329
[9]
A high-throughput liquid chromatography/tandem mass spectrometry method for screening glutathione conjugates using exact mass neutral loss acquisition
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Plumb, R
Liang, L
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Waters Corp MS Technol Ctr, Manchester M23 9LZ, Lancs, England
Liang, L
Yang, E
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0
引用数:
0
h-index:
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机构:
Waters Corp MS Technol Ctr, Manchester M23 9LZ, Lancs, England
Yang, E
[J].
RAPID COMMUNICATIONS IN MASS SPECTROMETRY,
2005,
19
(06)
: 798
-
804
[10]
Chen WCG, 2001, ADV EXP MED BIOL, V500, P521
←
1
2
3
4
5
6
7
8
9
→
共 85 条
[1]
Anders MW, 2001, ADV EXP MED BIOL, V500, P113
[2]
Skin sensitization: Reaction mechanistic applicability domains for structure-activity relationships
Aptula, AO
论文数:
0
引用数:
0
h-index:
0
机构:
Unilever Res Labs Colworth, SEAC, Sharnbrook MK44 1LQ, Beds, England
Unilever Res Labs Colworth, SEAC, Sharnbrook MK44 1LQ, Beds, England
Aptula, AO
论文数:
引用数:
h-index:
机构:
Patlewicz, G
Roberts, DW
论文数:
0
引用数:
0
h-index:
0
机构:
Unilever Res Labs Colworth, SEAC, Sharnbrook MK44 1LQ, Beds, England
Roberts, DW
[J].
CHEMICAL RESEARCH IN TOXICOLOGY,
2005,
18
(09)
: 1420
-
1426
[3]
Carcinogenicity of the aromatic amines: From structure-activity relationships to mechanisms of action and risk assessment
Benigni, R
论文数:
0
引用数:
0
h-index:
0
机构:
Ist Super Sanita, Comparat Toxicol & Ecotoxicol Lab, I-00161 Rome, Italy
Ist Super Sanita, Comparat Toxicol & Ecotoxicol Lab, I-00161 Rome, Italy
Benigni, R
Passerini, L
论文数:
0
引用数:
0
h-index:
0
机构:
Ist Super Sanita, Comparat Toxicol & Ecotoxicol Lab, I-00161 Rome, Italy
Ist Super Sanita, Comparat Toxicol & Ecotoxicol Lab, I-00161 Rome, Italy
Passerini, L
[J].
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH,
2002,
511
(03)
: 191
-
206
[4]
Toxicity testing: creating a revolution based on new technologies
Bhogal, N
论文数:
0
引用数:
0
h-index:
0
机构:
FRAME, Nottingham NG1 4EE, England
FRAME, Nottingham NG1 4EE, England
Bhogal, N
Grindon, C
论文数:
0
引用数:
0
h-index:
0
机构:
FRAME, Nottingham NG1 4EE, England
FRAME, Nottingham NG1 4EE, England
Grindon, C
Combes, R
论文数:
0
引用数:
0
h-index:
0
机构:
FRAME, Nottingham NG1 4EE, England
FRAME, Nottingham NG1 4EE, England
Combes, R
Balls, M
论文数:
0
引用数:
0
h-index:
0
机构:
FRAME, Nottingham NG1 4EE, England
FRAME, Nottingham NG1 4EE, England
Balls, M
[J].
TRENDS IN BIOTECHNOLOGY,
2005,
23
(06)
: 299
-
307
[5]
Quinoids, quinoid radicals, and phenoxyl radicals formed from estrogens and antiestrogens
Bolton, JL
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Illinois, Coll Pharm, Dept Med Chem & Pharmacognosy, Chicago, IL 60612 USA
Univ Illinois, Coll Pharm, Dept Med Chem & Pharmacognosy, Chicago, IL 60612 USA
Bolton, JL
[J].
TOXICOLOGY,
2002,
177
(01)
: 55
-
65
[6]
BOSWELLSMITH V, 2005, CURR OPIN INV DRUGS, V6, P1136
[7]
Early prediction of drug metabolism and toxicity: systems biology approach and modeling
Bugrim, A
论文数:
0
引用数:
0
h-index:
0
机构:
GeneCo, St Joseph, MI 49085 USA
Bugrim, A
Nikolskaya, T
论文数:
0
引用数:
0
h-index:
0
机构:
GeneCo, St Joseph, MI 49085 USA
Nikolskaya, T
Nikolsky, Y
论文数:
0
引用数:
0
h-index:
0
机构:
GeneCo, St Joseph, MI 49085 USA
Nikolsky, Y
[J].
DRUG DISCOVERY TODAY,
2004,
9
(03)
: 127
-
135
[8]
Comparison of the computer programs DEREK and TOPKAT to predict bacterial mutagenicity
Cariello, NF
论文数:
0
引用数:
0
h-index:
0
机构:
GlaxoSmithKline Inc, Safety Assessment, Res Triangle Pk, NC 27709 USA
Cariello, NF
Wilson, JD
论文数:
0
引用数:
0
h-index:
0
机构:
GlaxoSmithKline Inc, Safety Assessment, Res Triangle Pk, NC 27709 USA
Wilson, JD
Britt, BH
论文数:
0
引用数:
0
h-index:
0
机构:
GlaxoSmithKline Inc, Safety Assessment, Res Triangle Pk, NC 27709 USA
Britt, BH
Wedd, DJ
论文数:
0
引用数:
0
h-index:
0
机构:
GlaxoSmithKline Inc, Safety Assessment, Res Triangle Pk, NC 27709 USA
Wedd, DJ
Burlinson, B
论文数:
0
引用数:
0
h-index:
0
机构:
GlaxoSmithKline Inc, Safety Assessment, Res Triangle Pk, NC 27709 USA
Burlinson, B
Gombar, V
论文数:
0
引用数:
0
h-index:
0
机构:
GlaxoSmithKline Inc, Safety Assessment, Res Triangle Pk, NC 27709 USA
Gombar, V
[J].
MUTAGENESIS,
2002,
17
(04)
: 321
-
329
[9]
A high-throughput liquid chromatography/tandem mass spectrometry method for screening glutathione conjugates using exact mass neutral loss acquisition
Castro-Perez, J
论文数:
0
引用数:
0
h-index:
0
机构:
Waters Corp MS Technol Ctr, Manchester M23 9LZ, Lancs, England
Castro-Perez, J
Plumb, R
论文数:
0
引用数:
0
h-index:
0
机构:
Waters Corp MS Technol Ctr, Manchester M23 9LZ, Lancs, England
Plumb, R
Liang, L
论文数:
0
引用数:
0
h-index:
0
机构:
Waters Corp MS Technol Ctr, Manchester M23 9LZ, Lancs, England
Liang, L
Yang, E
论文数:
0
引用数:
0
h-index:
0
机构:
Waters Corp MS Technol Ctr, Manchester M23 9LZ, Lancs, England
Yang, E
[J].
RAPID COMMUNICATIONS IN MASS SPECTROMETRY,
2005,
19
(06)
: 798
-
804
[10]
Chen WCG, 2001, ADV EXP MED BIOL, V500, P521
←
1
2
3
4
5
6
7
8
9
→