Preparation of acyl fluorides with hydrogen fluoride-pyridine and 1,3-dicyclohexylcarbodiimide

被引：50

作者：

Chen, CP ^{[1
]}

Chien, CT ^{[1
]}

Su, CH ^{[1
]}

机构：

[1] Natl Dong Hwa Univ, Dept Chem, Hualien 974, Taiwan

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2002年 / 115卷 / 01期

关键词：

acyl fluoride; hydrogen fluoride-pyridine; 1,3-dicyclohexylcarbodiimide;

D O I：

10.1016/S0022-1139(02)00004-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

This work presents an efficient procedure for preparing acyl fluorides by simply reacting carboxylic acid with hydrogen fluoride-pyridine and 1,3-dicyclohexylcarbodiimide (DCC) in dichloromethane. The acyl fluorides were converted in situ to the corresponding benzyl carboxylic esters by adding benzyl alcohol and triethylamine to the reaction mixture. (C) 2002 Elsevier Science B.V. All rights reserved.

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页码：75 / 77

页数：3

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