Synthesis of Epoxides by Palladium-Catalyzed Reactions of Tertiary Allyl Alcohols with Aryl or Alkenyl Halides

被引：52

作者：

Hayashi, Sayuri ^{[1
]}

Yorimitsu, Hideki ^{[1
]}

Oshima, Koichiro ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Nishikyo Ku, Kyoto 6158510, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 131卷 / 06期

关键词：

ONE-POT SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; ASYMMETRIC EPOXIDATION; CARBOETHERIFICATION; TETRAHYDROFURANS; CARBOAMINATION; INSERTION; SCOPE;

D O I：

10.1021/ja8084065

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel synthetic method for the preparation of tri- or tetrasubstituted epoxides is reported. Treatment of readily available tertiary allyl alcohol with aryl or alkenyl, halide under palladium catalysis resulted in arylative cyclization to form the epoxide. The reaction includes intramotecular C-O bond and intermolecular C-C bond construction.

引用

页码：2052 / +

页数：3

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