Highly enantioselective hydrogenation of enamides catalyzed by rhodium-monodentate phosphoramidite complex

被引：62

作者：

Jia, X

Guo, RW

Li, XS

Yao, XS

Chan, ASC ^{[1
]}

机构：

[1] Hong Kong Polytech Univ, Open Lab Chirotechnol, Inst Mol Technol Drug Discovery & Synth, Hong Kong, Hong Kong, Peoples R China

[2] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Hong Kong, Peoples R China

[3] Shenyang Pharmaceut Univ, Shenyang, Peoples R China

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 32期

关键词：

asymmetric hydrogenation; enamides; rhodium complex; monophos;

D O I：

10.1016/S0040-4039(02)01142-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The monodentate phosphoramidite ligand monophos was used in the Rh-catalyzed asymmetric hydrogenation of enamides to give high enantioselectivities (up to 96% ee). (C) 2002 Published by Elsevier Science Ltd.

引用

页码：5541 / 5544

页数：4

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