Functionalization of 2-alkylidenetetrahydrofurans and 2-alkylidenepyrrolidines by palladium(0)-catalyzed cross-coupling reactions

被引：11

作者：

Bellur, E ^{[1
]}

Langer, P ^{[1
]}

机构：

[1] Ernst Moritz Arndt Univ Greifswald, Inst Chem & Biochem, D-17487 Greifswald, Germany

来源：

SYNLETT | 2004年 / 12期

关键词：

bromination; cross-coupling; palladium; pyrrolidines; tetrahydrofurans;

D O I：

10.1055/s-2004-830892

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Alkylidenetetrahydrofurans and 2-alkylidenepyrrolidines were efficiently functionalized by bromination of the exo-cyclic double bond and subsequent palladium-catalyzed cross-coupling reactions.

引用

页码：2169 / 2171

页数：3

共 33 条

[1] STUDIES ON CHEMISTRY OF LICHENS .14. STRUCTURE OF CALYCIN [J].

AKERMARK, B .

ACTA CHEMICA SCANDINAVICA, 1961, 15 (08) :1695-&

[2]

ARAI H, 1989, CHEM PHARM BULL, V12, P3229

[3] A novel catalytic and highly enantioselective approach for the synthesis of optically active carbohydrate derivatives [J].

Audrain, H ;

Thorhauge, J ;

Hazell, RG ;

Jorgensen, KA .

JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (15) :4487-4497

[4] STUDIES ON THE NACTINS - TOTAL SYNTHESIS OF (+/-)-TERT-BUTYL 8-O-(TERT-BUTYLDIMETHYLSILYL)NONACTATE [J].

BARRETT, AGM ;

SHETH, HG .

JOURNAL OF ORGANIC CHEMISTRY, 1983, 48 (25) :5017-5022

[5] ENANTIODIVERGENT SYNTHESES OF (+)-NONACTIC AND (-)-NONACTIC ACID AND THE TOTAL SYNTHESIS OF NONACTIN [J].

BARTLETT, PA ;

MEADOWS, JD ;

OTTOW, E .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (18) :5304-5311

[6] Syntheses and biological evaluation of 3-substituted amino-1-aryl-6-hydroxy-hex-2-ene-1-ones as antioxidant and hypolipidemic agents [J].

Batra, S ;

Srivastava, S ;

Singh, K ;

Chander, R ;

Khanna, AK ;

Bhaduri, AP .

BIOORGANIC & MEDICINAL CHEMISTRY, 2000, 8 (08) :2195-2209

[7] A NOVEL PYRROLE SYNTHESIS [J].

BERTSCHY, H ;

MEUNIER, A ;

NEIER, R .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1990, 29 (07) :777-778

[8] PREPARATION OF ACYLTETRONIC ACIDS USING TERT-BUTYL ACETOTHIOACETATE - TOTAL SYNTHESIS OF THE FUNGAL METABOLITES CAROLIC, CARLOSIC, AND CARLIC ACIDS [J].

BOOTH, PM ;

FOX, CMJ ;

LEY, SV .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1987, (01) :121-129

[9] SYNTHESIS AND PROPERTIES OF (E)-2-(ACYLMETHYLENE)TETRAHYDROFURANS - 6-HYDROXY-1,3-HEXANEDIONE EQUIVALENTS [J].

DETTY, MR .

JOURNAL OF ORGANIC CHEMISTRY, 1979, 44 (13) :2073-2077

[10] Alkylation of vinyl sulfones as a route to 2-alkylidene tetrahydrofurans [J].

Edwards, GL ;

Sinclair, DJ .

TETRAHEDRON LETTERS, 1999, 40 (20) :3933-3934

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