Electroorganic synthesis of new benzofuro[2,3-d]pyrimidine derivatives

被引：93

作者：

Nematollahi, D ^{[1
]}

Goodarzi, H ^{[1
]}

机构：

[1] Univ Bu Ali Sina, Fac Sci, Dept Chem, Hamadan, Iran

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 14期

关键词：

D O I：

10.1021/jo0200623

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Electrochemical oxidation of 3,4-dihydroxybenzoic acid (1) in the presence of 1,3-dimethylbarbituric acid (2) and 1,3-diethyl-2-thiobarbituric acid (3) as nucleophiles in aqueous solution has been studied using cyclic voltammetry and controlled-potential coulometry. The results indicate that 1 via Michael reaction under electro-decarboxylation reaction converts to benzofuro[2,3-d]pyrimidine derivatives (6a, 6b). The electrochemical synthesis of 6a, 6b has been successfully performed in an undivided cell in good yields and purity.

引用

页码：5036 / 5039

页数：4

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