Redox polymer-based reagentless horseradish peroxidase biosensors Influence of the molecular structure of the polymer

被引：21

作者：

Guschin, Dmitrii A.

Sultanov, Yusif M.

Sharif-Zade, Nigar F.

Aliyev, Elchin H.

Efendiev, Ayaz A.

Schuhmann, Wolfgang

机构：

[1] Ruhr Univ Bochum, D-44780 Bochum, Germany

[2] Azerbaijan Natl Acad Sci, Inst Chem Problems, Baku, Azerbaijan

来源：

ELECTROCHIMICA ACTA | 2006年 / 51卷 / 24期

关键词：

amperometric biosensor; horseradish peroxidase; Os-bis-N,N-(2,2 '-bipyridil)-dichloride; poly(4-vinylpyridine); poly(4-vinylpyridine-co-butyl methacrylate);

D O I：

10.1016/j.electacta.2006.03.056

中图分类号：

O646 [电化学、电解、磁化学];

学科分类号：

081704 ;

摘要：

Reagentless amperometric biosensors were prepared using a variety of nitrogen donor groups containing co-polymers. The polymers were coordinated with Os-bis-N,N-(2,2'-bipyridil)-dichloride via a ligand exchange reaction thus assuring an efficient electron-transfer pathway between the polymer-entrapped horseradish peroxidase and the electrode surface by means of a sequence of electron-hopping steps. The impact of structural features of the polymer such as spacer length between the Os-complex and the polymer backbone or the ratio of 4-vinylpyridine and butylmethacrylate in a co-polymer on the activity of the horseradish peroxidase biosensors was investigated. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：5137 / 5142

页数：6

共 18 条

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