The significance of apoptosis in the liver

被引:18
作者
Benedetti, A [1 ]
Marucci, L [1 ]
机构
[1] Univ Ancona, Dept Gastroenterol, I-60020 Ancona, Italy
来源
LIVER | 1999年 / 19卷 / 06期
关键词
apoptosis; phagocytosis; mitochondria; viral hepatitis; cholestasis; alcoholic liver disease; allograft rejection; Wilson's disease; CCl4;
D O I
10.1111/j.1478-3231.1999.tb00077.x
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Apoptosis is a form of cell death which occurs in normal as well as in pathological tissues. We provide a description of the morphological changes during apoptosis and an overview of the role of apoptosis dysregulation in the pathogenesis of non-neoplastic liver diseases.
引用
收藏
页码:453 / 463
页数:11
相关论文
共 159 条
[1]  
ABREUMARTIN MT, 1995, J IMMUNOL, V155, P4147
[2]   APOPTOSIS IN THE HUMAN LIVER DURING ALLOGRAFT-REJECTION AND END-STAGE LIVER-DISEASE [J].
AFFORD, SC ;
HUBSCHER, S ;
STRAIN, AJ ;
ADAMS, DH ;
NEUBERGER, JM .
JOURNAL OF PATHOLOGY, 1995, 176 (04) :373-380
[3]   Islet rejection in perforin-deficient mice - The role of perforin and fas [J].
Ahmed, KR ;
Guo, TB ;
Gaal, KK .
TRANSPLANTATION, 1997, 63 (07) :951-957
[4]   Dendritic cells acquire antigen from apoptotic cells and induce class I restricted CTLs [J].
Albert, ML ;
Sauter, B ;
Bhardwaj, N .
NATURE, 1998, 392 (6671) :86-89
[5]   Role and mechanisms of action of acetylcholine in the regulation of rat cholangiocyte secretory functions [J].
Alvaro, D ;
Alpini, G ;
Jezequel, AM ;
Bassotti, C ;
Francia, C ;
Fraioli, F ;
Romeo, R ;
Marucci, L ;
LeSage, G ;
Glaser, SS ;
Benedetti, A .
JOURNAL OF CLINICAL INVESTIGATION, 1997, 100 (06) :1349-1362
[6]  
Aplin AE, 1998, PHARMACOL REV, V50, P197
[7]   Proteolysis and the biochemistry of life-or-death decisions [J].
Ashkenas, J ;
Werb, Z .
JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 183 (05) :1947-1951
[8]  
AUST S D, 1985, Journal of Free Radicals in Biology and Medicine, V1, P3, DOI 10.1016/0748-5514(85)90025-X
[9]   CHRONIC ETHANOL FEEDING INCREASES APOPTOSIS AND CELL-PROLIFERATION IN RAT-LIVER [J].
BARONI, GS ;
MARUCCI, L ;
BENEDETTI, A ;
MANCINI, R ;
JEZEQUEL, AM ;
ORLANDI, F .
JOURNAL OF HEPATOLOGY, 1994, 20 (04) :508-513
[10]  
BATTERSBY C, 1974, SURGERY, V76, P617