Applied Nanotoxicology

被引:18
作者
Hobson, David W. [1 ]
Roberts, Stephen M. [2 ]
Shvedova, Anna A. [3 ]
Warheit, David B. [4 ]
Hinkley, Georgia K. [2 ]
Guy, Robin C. [5 ]
机构
[1] LoneStar PharmTox LLC, Bergheim, TX USA
[2] Univ Florida, Gainesville, FL USA
[3] NIOSH, CDC, Morgantown, WV USA
[4] Chemours Co, Wilmington, DE USA
[5] Robin Guy Consulting LLC, POB 830, Lake Forest, IL 60045 USA
关键词
nanotoxicology; nanomaterial toxicology; nanotechnology; nanoparticle; nanosafety; nanomaterial; WALLED CARBON NANOTUBES; OXIDATIVE STRESS; PULMONARY TOXICITY; TITANIUM-DIOXIDE; BIODISTRIBUTION; NANOPARTICLES; AGGLOMERATION; INFLAMMATION; NANOSPHERES; PARTICLES;
D O I
10.1177/1091581816628484
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Nanomaterials, including nanoparticles and nanoobjects, are being incorporated into everyday products at an increasing rate. These products include consumer products of interest to toxicologists such as pharmaceuticals, cosmetics, food, food packaging, household products, and so on. The manufacturing of products containing or utilizing nanomaterials in their composition may also present potential toxicologic concerns in the workplace. The molecular complexity and composition of these nanomaterials are ever increasing, and the means and methods being applied to characterize and perform useful toxicologic assessments are rapidly advancing. This article includes presentations by experienced toxicologists in the nanotoxicology community who are focused on the applied aspect of the discipline toward supporting state of the art toxicologic assessments for food products and packaging, pharmaceuticals and medical devices, inhaled nanoparticle and gastrointestinal exposures, and addressing occupational safety and health issues and concerns. This symposium overview article summarizes 5 talks that were presented at the 35th Annual meeting of the American College of Toxicology on the subject of Applied Nanotechnology.
引用
收藏
页码:5 / 16
页数:12
相关论文
共 57 条
  • [1] Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy
    Aggarwal, Parag
    Hall, Jennifer B.
    McLeland, Christopher B.
    Dobrovolskaia, Marina A.
    McNeil, Scott E.
    [J]. ADVANCED DRUG DELIVERY REVIEWS, 2009, 61 (06) : 428 - 437
  • [2] [Anonymous], DRAFT GUID IND DIET
  • [3] Guidance on the risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain EFSA Scientific Committee
    Antunovic, Boris
    Barlow, Susan
    Chesson, Andrew
    Flynn, Albert
    Hardy, Anthony
    Jany, Klaus-Dieter
    Jeger, Michael-John
    Knaap, Ada
    Kuiper, Harry
    Larsen, John-Christian
    Lovell, David
    Noerrung, Birgit
    Schlatter, Josef
    Silano, Vittorio
    Smulders, Frans
    Vannier, Philippe
    [J]. EFSA JOURNAL, 2011, 9 (05)
  • [4] Doxil® - The first FDA-approved nano-drug: Lessons learned
    Barenholz, Yechezkel
    [J]. JOURNAL OF CONTROLLED RELEASE, 2012, 160 (02) : 117 - 134
  • [5] Passive targeting of nanoparticles to cancer: A comprehensive review of the literature
    Bazak, Remon
    Houri, Mohamad
    El Achy, Samar
    Hussein, Wael
    Refaat, Tamer
    [J]. MOLECULAR AND CLINICAL ONCOLOGY, 2014, 2 (06) : 904 - 908
  • [6] Braun JH, 1997, J COATING TECHNOL, V69, P59
  • [7] A review of the prospects for polymeric nanoparticle platforms in oral insulin delivery
    Chen, Mei-Chin
    Sonaje, Kiran
    Chen, Ko-Jie
    Sung, Hsing-Wen
    [J]. BIOMATERIALS, 2011, 32 (36) : 9826 - 9838
  • [8] Barrier Properties of Gastrointestinal Mucus to Nanoparticle Transport
    Crater, Jason S.
    Carrier, Rebecca L.
    [J]. MACROMOLECULAR BIOSCIENCE, 2010, 10 (12) : 1473 - 1483
  • [9] Carbon Nanotubes: Present and Future Commercial Applications
    De Volder, Michael F. L.
    Tawfick, Sameh H.
    Baughman, Ray H.
    Hart, A. John
    [J]. SCIENCE, 2013, 339 (6119) : 535 - 539
  • [10] Engineered Nanoparticulate Drug Delivery Systems: The Next Frontier for Oral Administration?
    Diab, Roudayna
    Jaafar-Maalej, Chiraz
    Fessi, Hatem
    Maincent, Philippe
    [J]. AAPS JOURNAL, 2012, 14 (04): : 688 - 702