Further modification of the Hodge test to screen AmpC β-lactamase (CMY-1)-producing strains of Escherichia coli and Klebsiella pneumoniae

被引：41

作者：

Yong, D

Park, R

Yum, JH

Lee, K

Choi, EC

Chong, Y

机构：

[1] Yonsei Univ, Coll Med, Dept Clin Pathol, Seoul, South Korea

[2] Yonsei Univ, Coll Med, Res Inst Bacterial Resistance, Seoul, South Korea

[3] Seoul Natl Univ, Coll Pharm, Seoul, South Korea

来源：

JOURNAL OF MICROBIOLOGICAL METHODS | 2002年 / 51卷 / 03期

关键词：

CMY-1; Escherichia coli; Klebsiella pneumoniae; Hodge test; three-dimensional extract test;

D O I：

10.1016/S0167-7012(02)00053-2

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Cefoxitin-resistant Escherichia coli and Klebsiella pneumoniae are widespread in Korea. Significant proportions of them are considered to be CMY-1 producers. For effective screening of CMY-1 producers, the Hodge test was modified by using a cefoxitin disk and the performance was evaluated. The sensitivity and specifity of the test were 100% and 94.9%, respectively. The test was easier to perform than the three-dimensional extract test. This modified test should be suitable for screening CMY-producing strains of E. coli and K. pneumoniae. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：407 / 410

页数：4

共 8 条

[1] Comparative characterization of the cephamycinase bla(CMY-1) gene and its relationship with other beta-lactamase genes [J].