Patterns of inhaled antiinflammatory medication use in young underserved children with asthma

被引:47
作者
Butz, Arlene M.
Tsoukleris, Mona
Donithan, Michele
Hsu, Van Doren
Mudd, Kim
Zuckerman, Ilene H.
Bollinger, Mary E.
机构
[1] Johns Hopkins Univ, Sch Med, Dept Pediat, Baltimore, MD 21205 USA
[2] Univ Maryland, Sch Pharm, Dept Pharm Practice & Sci, Baltimore, MD 21201 USA
[3] Univ Maryland, Sch Pharm, Dept Pharmaceut Hlth Serv Res, Baltimore, MD 21201 USA
[4] Univ Maryland, Sch Med, Div Pediat Pulmonol & Allergy, Baltimore, MD 21201 USA
[5] Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA
关键词
asthma; children; preventive care; antiinflammatory; PEDIATRIC ASTHMA; PRIMARY-CARE; URBAN CHILDREN; UNITED-STATES; ADHERENCE; CORTICOSTEROIDS; PREVENTION; MANAGEMENT; THERAPY; EDUCATION;
D O I
10.1542/peds.2006-1630
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
BACKGROUND. Asthma guidelines advocate inhaled corticosteroids as the cornerstone treatment of persistent asthma, yet several studies report underuse of inhaled corticosteroids in children with persistent asthma. Moreover, few studies use objective pharmacy data as a measure of drug availability of asthma medications. We examined factors associated with the use of inhaled corticosteroids in young underserved children with persistent asthma using pharmacy records as their source of asthma medications. METHODS. This was a cross-sectional analysis of questionnaire and pharmacy record data over a 12-month period from participants enrolled in a randomized clinical trial of a nebulizer educational intervention. RESULTS. Although exposure to >= 1 inhaled corticosteroids refill was high at 72%, 1 of 5 children with persistent asthma had either no medication or only short-acting beta agonist fills for 12 months. Only 20% of children obtained >= 6 inhaled corticosteroids fills over 12 months. Obtaining >= 3 inhaled corticosteroids fills over 12 months was significantly associated with an increase in short-acting beta agonist fills and receiving specialty care in the regression models while controlling for child age, asthma severity, number of emergency department visits, having an asthma action plan, and seeking preventive care for the child's asthma. CONCLUSIONS. Overreliance on short-acting beta agonist and underuse of inhaled corticosteroid medications was common in this group of young children with persistent asthma. Only one fifth of children obtained sufficient controller medication fills.
引用
收藏
页码:2504 / 2513
页数:10
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