IGF-1 colocalizes with muscle satellite cells following acute exercise in humans

被引：21

作者：

Grubb, Amanda ^{[1
]}

Joanisse, Sophie ^{[1
]}

Moore, Daniel R. ^{[1
,2
]}

Bellamy, Leeann M. ^{[1
]}

Mitchell, Cameron J. ^{[1
]}

Phillips, Stuart M. ^{[1
]}

Parise, Gianni ^{[1
,3
]}

机构：

[1] McMaster Univ, Dept Kinesiol, Hamilton, ON L8S 4L8, Canada

[2] Univ Toronto, Fac Kinesiol & Phys Educ, Toronto, ON M5S 2W6, Canada

[3] McMaster Univ, Dept Med Phys & Appl Radiat Sci, Hamilton, ON L8S 4L8, Canada

来源：

APPLIED PHYSIOLOGY NUTRITION AND METABOLISM | 2014年 / 39卷 / 04期

关键词：

Pax7; IGF-1; acute exercise; SKELETAL-MUSCLE; REGULATORY FACTORS; EXPRESSION; REGENERATION; MYONUCLEAR; GROWTH; YOUNG; WOMEN;

D O I：

10.1139/apnm-2013-0430

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 [营养与食品卫生学];

摘要：

Insulin-like growth factor-1 (IGF-1) regulates stem cell proliferation and differentiation in vitro. The aim of this study was to quantify the change in satellite cell (SC) specific IGF-1 colocalization following exercise. We observed a significant increase (p < 0.05) in the percentage of SC with IGF-1 colocalization from baseline to 72 h after a bout of resistance exercise. This strongly supports a role for IGF-1 in human SC function following exercise.

引用

页码：514 / 518

页数：5

共 14 条

[1]

Cellular and molecular responses to increased skeletal muscle loading after irradiation [J].

Adams, GR ;

Caiozzo, VJ ;

Haddad, F ;

Baldwin, KM .

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2002, 283 (04) :C1182-C1195

[2]

Protein supplementation augments the adaptive response of skeletal muscle to resistance-type exercise training: a meta-analysis [J].

Cermak, Naomi M. ;

Res, Peter T. ;

de Groot, Lisette C. P. G. M. ;

Saris, Wim H. M. ;

van Loon, Luc J. C. .

AMERICAN JOURNAL OF CLINICAL NUTRITION, 2012, 96 (06) :1454-1464

[3]

Skeletal muscle IGF-I isoform expression in healthy women after isometric exercise [J].

Greig, Carolyn A. ;

Hameed, Mahjabeen ;

Young, Archie ;

Goldspink, Geoffrey ;

Noble, Brendon .

GROWTH HORMONE & IGF RESEARCH, 2006, 16 (5-6) :373-376

[4]

Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise [J].

Hameed, M ;

Orrell, RW ;

Cobbold, M ;

Goldspink, G ;

Harridge, SDR .

JOURNAL OF PHYSIOLOGY-LONDON, 2003, 547 (01) :247-254

[5]

Expression and splicing of the insulin-like growth factor gene in rodent muscle is associated with muscle satellite (stem) cell activation following local tissue damage [J].

Hill, M ;

Goldspink, G .

JOURNAL OF PHYSIOLOGY-LONDON, 2003, 549 (02) :409-418

[6]

Evidence for the contribution of muscle stem cells to nonhypertrophic skeletal muscle remodeling in humans [J].

Joanisse, Sophie ;

Gillen, Jenna B. ;

Bellamy, Leeann M. ;

McKay, Bryon R. ;

Tarnopolsky, Mark A. ;

Gibala, Martin. J. ;

Parise, Gianni .

FASEB JOURNAL, 2013, 27 (11) :4596-4605

[7]

Concomitant increases in myonuclear and satellite cell content in female trapezius muscle following strength training [J].

Kadi, F ;

Thornell, LE .

HISTOCHEMISTRY AND CELL BIOLOGY, 2000, 113 (02) :99-103

[8]

Co-expression of IGF-1 family members with myogenic regulatory factors following acute damaging muscle-lengthening contractions in humans [J].

McKay, Bryon R. ;

O'Reilly, Ciara E. ;

Phillips, Stuart M. ;

Tarnopolsky, Mark A. ;

Parise, Gianni .

JOURNAL OF PHYSIOLOGY-LONDON, 2008, 586 (22) :5549-5560

[9]

Muscular and Systemic Correlates of Resistance Training-Induced Muscle Hypertrophy [J].

Mitchell, Cameron J. ;

Churchward-Venne, Tyler A. ;

Bellamy, Leeann ;

Parise, Gianni ;

Baker, Steven K. ;

Phillips, Stuart M. .

PLOS ONE, 2013, 8 (10)

[10]

Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle [J].

Musarò, A ;

McCullagh, K ;

Paul, A ;

Houghton, L ;

Dobrowolny, G ;

Molinaro, M ;

Barton, ER ;

Sweeney, HL ;

Rosenthal, N .

NATURE GENETICS, 2001, 27 (02) :195-200

← 1 2 →