Antiyeast steroidal saponins from Yucca schidigera (Mohave yucca), a new anti-food-deteriorating agent

被引：96

作者：

Miyakoshi, M

Tamura, Y

Masuda, H

Mizutani, K

Tanaka, O

Ikeda, T

Ohtani, K

Kasai, R

Yamasaki, K

机构：

[1] Maruzen Pharmaceut Co Ltd, Onomichi, Hiroshima 7220062, Japan

[2] Hiroshima Univ, Fac Med, Inst Pharmaceut Sci, Minato Ku, Hiroshima 7348551, Japan

来源：

JOURNAL OF NATURAL PRODUCTS | 2000年 / 63卷 / 03期

关键词：

D O I：

10.1021/np9904354

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

A saponin fraction from the stems of Yucca schidigera (Mohave yucca) exhibited potent growth-inhibitory activities against certain food-deteriorating yeasts, film-forming yeasts, and dermatophytic yeasts and fungi. From this fraction, a number of new anti-yeast monodesmosidic spirostanol saponins, named schidigera-saponins A1 (1), A2 (2), A3 (3), B1 (4), C1 (5),C2 (6); 25(R and S) schidigera-saponins D1 (7), D2 (8), E1 (12), F1 (13); and 25(S) schidigera-saponins D3 (9), D4 (10), D5 (11), and F2 (14) were isolated, together with several related known saponins, and the structures were elucidated by spectroscopic methods (see Chart 1). The relationship between the antiyeast activities and the structures of these saponins is described.

引用

页码：332 / 338

页数：7

共 12 条

[1]

KAMEOKA H, 1993, 65 SPRING NAT M CHEM

[2]

STEROIDAL CONSTITUENTS OF YUCCA-SHIDIGERA PLANTS AND TISSUE-CULTURES [J].