Nephrotoxicity Associated with Intravenous Colistin (Colistimethate Sodium) Treatment at a Tertiary Care Medical Center

被引:291
作者
Hartzell, Joshua D. [1 ]
Neff, Robert [2 ]
Ake, Julie [1 ]
Howard, Robin [3 ]
Olson, Stephen [2 ]
Paolino, Kristopher [1 ]
Vishnepolsky, Mark [2 ]
Weintrob, Amy [1 ]
Wortmann, Glenn [1 ]
机构
[1] USA, Infect Dis Serv, Walter Reed Army Med Ctr, Washington, DC 20307 USA
[2] Walter Reed Army Med Ctr, Dept Med, Serv Nephrol, Washington, DC 20307 USA
[3] Walter Reed Army Med Ctr, Dept Clin Invest, Washington, DC 20307 USA
关键词
RESISTANT PSEUDOMONAS-AERUGINOSA; VENTILATOR-ASSOCIATED PNEUMONIA; NEGATIVE BACTERIAL-INFECTIONS; ACINETOBACTER-BAUMANNII; THERAPY; POLYMYXINS; DEFINITION; TOXICITY; EFFICACY; SAFETY;
D O I
10.1086/599225
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The incidence of acute renal failure, defined by the risk, injury, or failure criteria of the RIFLE criteria ( risk, injury, failure, loss, and end-stage kidney disease), in 66 patients who received colistimethate sodium was 45%, and 21% of patients stopped therapy because of nephrotoxicity. The RIFLE criteria should be used in the future to allow for comparison of nephrotoxicity among studies.
引用
收藏
页码:1724 / 1728
页数:5
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