Transmission of drug-resistant HIV after an occupational exposure despite postexposure prophylaxis with a combination drug regimen

被引:25
作者
Beltrami, EM
Luo, CC
de la Torre, N
Cardo, DM
机构
[1] CDCP, Natl Ctr Infect Dis, HIV Immunol & Diagnost Branch, Div AIDS STD & TB Lab Res, Atlanta, GA 30333 USA
[2] CDCP, Natl Ctr Infect Dis, Prevent & Evaluat Branch, Div Healthcare Qual Promot, Atlanta, GA 30333 USA
关键词
D O I
10.1086/502065
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
We documented a case of occupational human immunodeficiency virus (HIV) despite postexposure prophylaxis (PEP) with a combination drug regimen after percutaneous injury with a needle from a sharps disposal container in the hospital room of an HIV-infected patient. This failure of PEP with a combination drug regimen may have been related to antiretroviral drug resistance, other factors, or both. This case highlights the importance of preventing injury to prevent occupational transmission of HIV (Infect Control Hosp Epidemiol 2002;23:345-348).
引用
收藏
页码:345 / 348
页数:4
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