Phytochemical and medicinal importance of Ginkgo biloba L.

被引:122
作者
Mohanta, Tapan Kumar [1 ]
Tamboli, Yasinalli [2 ]
Zubaidha, P. K. [2 ]
机构
[1] Natl Inst Plant Genome Res, Lab 102, New Delhi 110067, India
[2] Swami Ramanand Teerth Marathwada Univ, Sch Chem Sci, Nanded 431606, Maharashtra, India
关键词
Ginkgo biloba L; Alzheimer's; ginkgolide; bilobalide; EGb; 761; EXTRACT; LEAVES;
D O I
10.1080/14786419.2013.879303
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Ginkgo biloba L., also popularly known as living fossil, possesses a variety of biological and pharmacological activities. The leaf extract of G. biloba L. (EGb 761) has been used for years to treat age-related memory-deficit problems, including Alzheimer's and dementia. Experimental and clinical studies have revealed its beneficial effects on a wide range of pathological conditions including hepatoprotective, photoprotective effects, DNA repair mechanism, antioxidant and anti-inflammatory activities. Recent studies have also suggested that leaf extract of G. biloba L. may exert beneficial effects on cancer. This review focuses on recent scientific evidence of the reported medicinal effects of G. biloba L.
引用
收藏
页码:746 / 752
页数:7
相关论文
共 40 条
  • [1] Agnes CF, 2011, J ALTERN COMPLEM MED, V17, P513
  • [2] [Anonymous], 2011, CHIN J CHIN MAT MED, DOI DOI 10.4268/CJCMM20111628
  • [3] Alleviating neuropsychiatric symptoms in dementia: the effects of Ginkgo biloba extract EGb 761®. Findings from a randomized controlled trial
    Bachinskaya, Natalia
    Hoerr, Robert
    Ihl, Ralf
    [J]. NEUROPSYCHIATRIC DISEASE AND TREATMENT, 2011, 7 : 209 - 215
  • [4] The Effect of Ginkgo biloba Extract on Mitochondrial Oxidative Phosphorylation in the Normal and Ischemic Rat Heart
    Bernatoniene, Jurga
    Majiene, Daiva
    Peciura, Rimantas
    Laukeviciene, Ale
    Bernatoniene, Ruta
    Mekas, Tauras
    Kasauskas, Arturas
    Kopustinskiene, Dalia
    [J]. PHYTOTHERAPY RESEARCH, 2011, 25 (07) : 1054 - 1060
  • [5] Protective effect of Ginkgo biloba extract on liver damage by a single dose of CCl4 in male rats
    Chavez-Morales, R. M.
    Jaramillo-Juarez, F.
    Posadas del Rio, F. A.
    Reyes-Romero, M. A.
    Rodriguez-Vazquez, M. L.
    Martinez-Saldana, M. C.
    [J]. HUMAN & EXPERIMENTAL TOXICOLOGY, 2011, 30 (03) : 209 - 216
  • [6] A Novel Anti-Inflammatory Role for Ginkgolide B in Asthma via Inhibition of the ERK/MAPK Signaling Pathway
    Chu, Xiao
    Ci, Xinxin
    He, Jiakang
    Wei, Miaomiao
    Yang, Xiaofeng
    Cao, Qingjun
    Li, Hongyu
    Guan, Shuang
    Deng, Yanhong
    Pang, Daxin
    Deng, Xuming
    [J]. MOLECULES, 2011, 16 (09): : 7634 - 7648
  • [7] Cohen A, 1997, P APA ANN M 1997
  • [8] Dal BE, 2011, PHYTOTHER RES, V25, P1854
  • [9] Ginkgo biloba extracts and cancer:: a research area in its infancy
    DeFeudis, FV
    Papadopoulos, V
    Drieu, K
    [J]. FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2003, 17 (04) : 405 - 417
  • [10] DeFeudis FV, 1991, Ginkgo biloba extract (EGb 761): pharmacological activities and clinical applications, P68