The bad seed: PDGF receptors link adult neural progenitors to glioma stem cells

被引：24

作者：

Kesari, Santosh ^{[1
]}

Stiles, Charles D. ^{[1
]}

机构：

[1] Harvard Univ, Dana Farber Canc Ctr, Program Neuro Oncol, Boston, MA 02115 USA

来源：

NEURON | 2006年 / 51卷 / 02期

关键词：

D O I：

10.1016/j.neuron.2006.07.001

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

引用

页码：151 / 153

页数：3

共 12 条

[1] Glial progenitors in adult white matter are driven to form malignant gliomas by platelet-derived growth factor-expressing retroviruses [J].

Assanah, Marcela ;

Lochhead, Richard ;

Ogden, Alfred ;

Bruce, Jeffrey ;

Goldman, James ;

Canoll, Peter .

JOURNAL OF NEUROSCIENCE, 2006, 26 (25) :6781-6790

[2] Subventricular zone astrocytes are neural stem cells in the adult mammalian brain [J].

Doetsch, F ;

Caillé, I ;

Lim, DA ;

García-Verdugo, JM ;

Alvarez-Buylla, A .

CELL, 1999, 97 (06) :703-716

[3] The PDGF family: four gene products form five dimeric isoforms [J].

Fredriksson, L ;

Li, H ;

Eriksson, U .

CYTOKINE & GROWTH FACTOR REVIEWS, 2004, 15 (04) :197-204

[4] PDGFRα-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling [J].

Jackson, Erica L. ;

Garcia-Verdugo, Jose Manuel ;

Gil-Perotin, Sara ;

Roy, Monica ;

Quinones-Hinojosa, Alfredo ;

VandenBerg, Scott ;

Alvarez-Buylla, Arturo .

NEURON, 2006, 51 (02) :187-199

[5] Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells [J].

Kondo, T ;

Raff, M .

GENES & DEVELOPMENT, 2004, 18 (23) :2963-2972

[6] Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines [J].

Lee, Jeongwu ;

Kotliarova, Svetlana ;

Kotliarov, Yuri ;

Li, Aiguo ;

Su, Qin ;

Donin, Nicholas M. ;

Pastorino, Sandra ;

Purow, Benjamin W. ;

Christopher, Neil ;

Zhang, Wei ;

Park, John K. ;

Fine, Howard A. .

CANCER CELL, 2006, 9 (05) :391-403

[7] Olig2 and Ngn2 function in opposition to modulate gene expression in motor neuron progenitor cells [J].

Lee, SK ;

Lee, B ;

Ruiz, EC ;

Pfaff, SL .

GENES & DEVELOPMENT, 2005, 19 (02) :282-294

[8] Development of NG2 neural progenitor cells requires Olig gene function [J].

Ligon, Keith L. ;

Kesari, Santosh ;

Kitada, Masaaki ;

Sun, Tao ;

Arnett, Heather A. ;

Alberta, John A. ;

Anderson, David J. ;

Stiles, Charles D. ;

Rowitch, David H. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (20) :7853-7858

[9] The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas [J].

Ligon, KL ;

Alberta, JA ;

Kho, AT ;

Weiss, J ;

Kwaan, MR ;

Nutt, CL ;

Louis, DN ;

Stiles, CD ;

Rowitch, DH .

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2004, 63 (05) :499-509

[10]

Lokker NA, 2002, CANCER RES, V62, P3729

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