Reactions of trifluorovinyllithium and 1-chloro-2,2-difluorovinyllithium: the synthesis of fluorinated heterocycles

被引：20

作者：

Burdon, J

Coe, PL

Haslock, IB

Powell, RL

机构：

[1] UNIV BIRMINGHAM, SCH CHEM, BIRMINGHAM B15 2TT, W MIDLANDS, ENGLAND

[2] ICI KLEA BUSINESS, RUNCORN WA7 4QD, CHESHIRE, ENGLAND

来源：

JOURNAL OF FLUORINE CHEMISTRY | 1997年 / 85卷 / 02期

关键词：

134a; 133a; 1-chloro-2,2-difluorovinyllithium; hydrochlorofluorocarbon; hydrofluorocarbon; quinolines; 2-trifluoromethylaniline; trifluorovinyllithium;

D O I：

10.1016/S0022-1139(97)00077-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Trifluorovinyllithium (from 1,1,1,2-tetrafluoroethane [HFC-134a]) reacted with 2-trifluoromethylaniline at -78 degrees C to give 1,2,3-trifluoroquinoline in moderate to good yield. In a similar reaction, 1-chlorodifluorovinyllithium (from 1-chloro-2,2,2-trifluoroethane [HCFC-133a]) yielded 2-chloro-1,3-difluoroquinoline. (C) 1997 Elsevier Science S.A.

引用

页码：151 / 153

页数：3

共 6 条

[1]

BANKS RE, 1994, ORGANOFLUROINE CHEM, P502

[2]

BEY P, 1991, ACS SYM SER, V456, P105

[3] The hydrofluorocarbon 1,1,1,2-tetrafluoroethane (HFC-134a) as a ready source of trifluorovinyllithium [J].