In vitro characterization and in vivo properties of a carbonated apatite bone cement

被引:200
作者
Khairoun, I
Magne, D
Gauthier, O
Bouler, JM
Aguado, E
Daculsi, G
Weiss, P
机构
[1] Fac Chirurg Dent, Lab Rech Mat Interet Biol, INSERM 9903, F-44042 Nantes 01, France
[2] Ecole Natl vet Nantes, Lab Chirurg, F-44307 Nantes, France
来源
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH | 2002年 / 60卷 / 04期
关键词
calcium phosphate cement; carbonated apatite; monetite; bone regeneration;
D O I
10.1002/jbm.10132
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This study evaluated the in vivo behavior of an injectable calcium phosphate bone cement implanted in bone defects at the distal end of rabbit femora. After 3 weeks, samples were harvested and processed for undecalcified sectioning. Scanning electron microscopy, transmission electron microscopy, and Fourier transform infrared microspectroscopy showed direct contact of bone and cement without soft tissue interposition, biocompatibility, and bioactivity with osteoconductive properties. (C) 2002 Wiley Periodicals, Inc.
引用
收藏
页码:633 / 642
页数:10
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