Stable weight during lamotrigine therapy: A review of 32 studies

被引：56

作者：

Devinsky, O

Vuong, A

Hammer, A

Barrett, PS

机构：

[1] NYU, Med Ctr, Dept Neurol, New York, NY USA

[2] Glaxo Wellcome Inc, Res Triangle Pk, NC 27709 USA

来源：

NEUROLOGY | 2000年 / 54卷 / 04期

关键词：

antiepileptic drugs; lamotrigine; body weight;

D O I：

10.1212/WNL.54.4.973

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A side effect associated with the use of some antiepileptic drugs (AEDs) is change in body weight. To evaluate the effect of lamotrigine on body weight in adult patients with epilepsy, we conducted a retrospective review of data from 463 patients treated with lamotrigine in 32 clinical trials. Mean daily dose was 259 (+/-155) mg and duration of therapy was 318 (+/-87) days. The mean change in body weight was 0.5 (+/-5) kg. Lamotrigine was associated with stable body weight in patients with epilepsy.

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收藏

页码：973 / 975

页数：3

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